Synthesis of peptidinol adenylates

Article abstract of DOI:10.1080/07328319808004322

Peptidinol adenylates were assembled by condensing the carboxyl group of N-blocked peptides with the alkylamino group of leucinol 5' adenosine phosphodiester. The latter was prepared as protected precursor from adenosine and leucinol by phosphite chemistry. The title compounds, which mimic aminoacyl adenylates, are designed to penetrate microorganisms via peptide permeases and to interfere with genetic translation.

Full text of DOI:10.1080/07328319808004322

This article was downloaded by: [Gazi University]
On: 01 May 2015, At: 01:37
Publisher: Taylor & Francis
Informa Ltd Registered in England and Wales Registered Number: 1072954 Registered
office: Mortimer House, 37-41 Mortimer Street, London W1T 3JH, UK
Nucleosides and Nucleotides
Publication details, including instructions for authors and
subscription information:
http://www.tandfonline.com/loi/lncn19
Synthesis of Peptidinol Adenylates
Annett Kreimeyer a b & Philippe Marliere a
a Unité de Biochimie Cellulaire , URA CNRS1129 Institut Pasteur, 28
rue du Dr. Roux, Paris, 75015, France
b Université de Louis Pasteur, Faculté de Pharmacie , 74, route du
Rhin, Illkirch, 67401, France
Published online: 16 Aug 2006.
To cite this article: Annett Kreimeyer & Philippe Marliere (1998) Synthesis of Peptidinol Adenylates,
Nucleosides and Nucleotides, 17:12, 2339-2350, DOI: 10.1080/07328319808004322
To link to this article: http://dx.doi.org/10.1080/07328319808004322
PLEASE SCROLL DOWN FOR ARTICLE
Taylor & Francis makes every effort to ensure the accuracy of all the information (the
“Content”) contained in the publications on our platform. However, Taylor & Francis,
our agents, and our licensors make no representations or warranties whatsoever as to
the accuracy, completeness, or suitability for any purpose of the Content. Any opinions
and views expressed in this publication are the opinions and views of the authors,
and are not the views of or endorsed by Taylor & Francis. The accuracy of the Content
should not be relied upon and should be independently verified with primary sources
of information. Taylor and Francis shall not be liable for any losses, actions, claims,
proceedings, demands, costs, expenses, damages, and other liabilities whatsoever or
howsoever caused arising directly or indirectly in connection with, in relation to or arising
out of the use of the Content.
This article may be used for research, teaching, and private study purposes. Any
substantial or systematic reproduction, redistribution, reselling, loan, sub-licensing,
systematic supply, or distribution in any form to anyone is expressly forbidden. Terms &
Conditions of access and use can be found at http://www.tandfonline.com/page/terms-
and-conditions