Journal of labelled compounds and radiopharmaceuticals p. 1127 - 1143 (1998)
Update date:2022-08-04
Topics:
Fellows, Ian
Carr, Richard M.
DeBoeck, Nigel
Montgomery, Stephen
Waterhouse, Ian
Sutherland, Derek R.
Methods for the synthesis of isotopically labelled N-methyl amines using the target amine and isotopically labelled methyl iodide in a quaternisation/dequaternisation strategy are described. The method has been further refined to allow the synthesis of such amines without any isotopic dilution.
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