Journal of Medicinal Chemistry p. 4239 - 4249 (1999)
Update date:2022-07-29
Topics:
Hu, Lain-Yen
Ryder, Todd R.
Rafferty, Michael F.
Feng, M. Rose
Lotarski, Susan M.
Rock, David M.
Sinz, Michael
Stoehr, Sally J.
Taylor, Charles P.
Weber, Mark L.
Bowersox, S. Scott
Miljanich, George P.
Millerman, Elizabeth
Wang, Yong-Xiang
Szoke, Balazs G.
In this article, the rationale for the design, synthesis, and biological evaluation of a series of N-type voltage-sensitive calcium channel (VSCC) blockers is described. N-Type VSCC blockers, such as ziconotide, have shown utility in several models of str
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