Heterocycles p. 2601 - 2610 (1998)
Update date:2022-08-05
Topics:
Saladino, Raffaele
Stasi, Luigi
Volpe, Gabriele
Nicoletti, Rosario
Botta, Maurizio
Dimethylphenylsilyllithium (PhMe2SiLi) reacts with 5-substituted 1,3-dimethyluracils by selective addition at the electrophilic C-6 position of the uracil ring to give the corresponding 6-dimethylphenylsilyl-5,6-dihydrouracil derivatives. The reaction of PhMe2SiLi with 6-substituted 1,3-dimethyluracils showed a different selectivity, and an unusual addition at the C-5 position was observed. This synthetic procedure appears to be an efficient entry to a new class of highly functionalized 5,6-dihydro-1,3-dimethyluraciIs characterized by the presence of a silicon substituent selectively introduced at the C-5 and C-6 positions of the uracil ring.
View MoreWuhan Silworld Chemical Co.,Ltd
website:http://www.silworldchemical.com
Contact:+86-27-85613400
Address:No.198 jiangjun Road, Wuhan,China 430033
Taizhou Sunny Chemical Co.,Ltd
Contact:+86-523-86920899 +86-13951172783
Address:No.11 Xingyuang road, Gaoyong Chemical Industry Park, Gaogang Jiangsu China
Changzhou BaoKang Pharmaceutical & Chemical Co., Ltd
Contact:(86) 519-88782201 88784080 88785278
Address:Henglin town, changzhou,Jiangsu
zhenjiang runjing high purity chemical co ltd
Contact:+86-511-83361155
Address:No.8.haixi road,international chemical park
Shijiazhuang Haitian Amino Acid Co., Ltd.
Contact:+86-311-88908111
Address:Shijiazhuang Hebei province,China
Doi:10.1021/jm980605u
(1999)Doi:10.1016/S0040-4039(98)80052-X
(1999)Doi:10.1016/j.polymer.2016.06.066
(2016)Doi:10.1016/j.molstruc.2018.11.068
(2019)Doi:10.1016/j.tet.2015.09.007
(2015)Doi:10.1016/S0040-4039(99)00055-6
(1999)