Synthesis of optically active 2-chloromethyl-2-oxazolines by the ortho- ester condensation method using triethyl orthochloroacetate

DOI: 10.3987/COM-98-8407

Source and publish data:

Heterocycles p. 373 - 378 (1999)

Update date:2022-08-03

Topics:

Authors:

Kamata, Kazuyuki

Sato, Hideki

Takagi, Emi

Agata, Isao

Meyers Meyers

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Article abstract of DOI:10.3987/COM-98-8407

A set of optically active 2-chloromethyl-2-oxazolines was synthesized by condensation of optically active 2-amino alcohols with triethyl orthochloroacetate which was prepared conveniently from triethyl orthoacetate by chlorination using tert-butyl hypochlorite.

Full text of DOI:10.3987/COM-98-8407

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Product name:Oxazole, 2-(chloromethyl)-4,5-dihydro-4-(phenylmethyl)-, (4S)-

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