6-thioguanine in peptide nucleic acids. Synthesis and hybridization properties

Article abstract of DOI:10.1080/07328319908045589

The synthesis of N-((2-amino-6-benzylthiopurine-9-yl)acetyl)-N-(2- tBocaminoethyl)glycine 4 and its incorporation into a peptide nucleic acid (PNA) oligomer are described. Introduction of a single 6-thioguanine residue (6sG) in the PNA of a 10-mer PNA:DNA

Full text of DOI:10.1080/07328319908045589

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6-Thioguanine in Peptide Nucleic Acids.
Synthesis and Hybridization Properties
Henrik F. Hansen a , Leif Christensen b , Otto Dahl a & Peter E.
Nielsen b
a Department of Chemistry , The H. C. Ørsted Institute, University of
Copenhagen , Universitetsparken 5, DK-2100, Copenhagen, Denmark
b Institute of Medicinal Biochemistry and Genetics, The Panum
Institute, University of Copenhagen , Blegdamsvej 3c, DK-2200,
Copenhagen, Denmark
Published online: 04 Oct 2006.
To cite this article: Henrik F. Hansen , Leif Christensen , Otto Dahl & Peter E. Nielsen (1999) 6-
Thioguanine in Peptide Nucleic Acids. Synthesis and Hybridization Properties, Nucleosides and
Nucleotides, 18:1, 5-9, DOI: 10.1080/07328319908045589
To link to this article: http://dx.doi.org/10.1080/07328319908045589
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