Bioorganic and Medicinal Chemistry Letters p. 249 - 254 (1999)
Update date:2022-08-04
Topics:
Auberson, Yves P.
Acklin, Pierre
Bischoff, Serge
Moretti, Robert
Ofner, Silvio
Schmutz, Markus
Veenstra, Siem J.
N-Substituted 5-aminomethylquinoxalinediones containing carboxy or phosphonic acids yield potent and selective AMPA and/or NMDA (glycine- binding site) antagonists. Phosphonic acid derivatives are particularly water-soluble and display potent anticonvulsa
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