5'-C-tosyloxyalkylnucleosides. Models for oligonucleotide coupling with nucleophiles

Article abstract of DOI:10.1080/07328319908044777

5'-C-substituted nucleosides with an hydroxyalkyl chain are synthesized. The stereochemistry of the new stereogenic center is defined. After introduction of a tosyl group, dimer models are prepared to evaluate the conjugation with amines used as nucleophiles.

Full text of DOI:10.1080/07328319908044777

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Nucleosides and Nucleotides
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5′-C-Tosyloxyalkylnucleosides. Models
for Oligonucleotide Coupling with
Nucleophiles
V. Banuls a , V. Sarramegna a , C. Froment a , J M. Escudier a & L.
Gorrichon a
a Laboratoire de synthèse et physicochimie organique associé au
C.N.R.S. , Université Paul Sabatier, 118 route de Narbonne, 31062,
Toulouse, (France)
Published online: 04 Oct 2006.
To cite this article: V. Banuls , V. Sarramegna , C. Froment , J M. Escudier & L. Gorrichon (1999) 5′-
C-Tosyloxyalkylnucleosides. Models for Oligonucleotide Coupling with Nucleophiles, Nucleosides and
Nucleotides, 18:6-7, 1527-1529, DOI: 10.1080/07328319908044777
To link to this article: http://dx.doi.org/10.1080/07328319908044777
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