Fmoc protected peptide mimetic based on a cyclohexane framework and incorporation into angiotensin II

Article abstract of DOI:10.1016/S0040-4020(97)00779-5

1,3,5-syn substituted cyclohexane based amino acids have been prepared and incorporated into synthetic peptides to serve as scaffold mimicking the Val-Tyr-Ile sequence of angiotensin II. The conformationally constrained tripeptide mimetic holds potential