Bioorganic and Medicinal Chemistry Letters p. 743 - 748 (1999)
Update date:2022-07-29
Topics:
Vuligonda, Vidyasagar
Standeven, Andrew M.
Escobar, Maria
Chandraratna, Roshantha A. S.
The synthesis and biological activity of a novel series of tricyclic retinoic acid receptor antagonists are described. These compounds bind with high affinity to the RARs and are potent antagonists of retinoid function in in vitro and in vivo systems.
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