Chemical and Pharmaceutical Bulletin p. 554 - 556 (1999)
Update date:2022-08-05
Topics:
Itaya, Taisuke
Kanai, Tae
Takada, Yasutaka
Kaneko, Miki
Yasuhara, Kensuke
Fujii, Tozo
Methylation of adenine 3-oxide (8a) with MeI in AcNMe2 afforded 3- methoxyadenine (9a) in 44% yield. This compound (9a) underwent hydroxide-ion attack at the 2-position to give 2-hydroxyadenine (isoguanine) (10a) in 38% yield. A parallel reaction sequence starting from N6-benzyladenine 3-oxide (8c) and proceeding through N6-benzyl-3-methoxyadenine (9c) provided N6- benzyl-2-hydroxyadenine (10c) in 29% overall yield, together with a small amount of N6-benzyladenine (11c).
View MoreContact:+49-9398-993127
Address:Untertorstr. 27
Changzhou BaoKang Pharmaceutical & Chemical Co., Ltd
Contact:(86) 519-88782201 88784080 88785278
Address:Henglin town, changzhou,Jiangsu
Contact:86-571-87758773
Address:Room604 ,6F, Block A1-3 Xixi Plaza,No. 588 Wenyi West RD, Hangzhou,310012, China
shijiazhuang shuanglian chemical industry co.,ltd
Contact:0311-82190302
Address:Luquan Intersection , Shijiazhuang--Taiyuan Expressway，Shijiazhuang City
Beijing Mesochem Technology Co.,LTD
website:http://www.mesochem.com
Contact:0086-10-57862036
Address:2301, Floor 23, Building 9 Lippo Plaza, Yard 8 Ronghua Middle Road, ETDZ, Beijing, China
Doi:10.1021/jo9825097
(1999)Doi:10.1021/jo990390b
(1999)Doi:10.1016/S0277-5387(98)00405-7
(1999)Doi:10.1021/jo990069t
(1999)Doi:10.1002/jps.2600580320
(1969)Doi:10.1016/S0022-328X(98)01131-0
(1999)
