Tetrahedron p. 4843 - 4852 (1999)
Update date:2022-08-03
Topics:
Grehn, Leif
Ragnarsson, Ulf
Catalytic hydrogenolysis of 1-Boc-1-Ts-2-Z-hydrazine furnished 1-Boc-1- Ts-hydrazine as a stable crystalline solid. Although its nucleophilicity is considerably suppressed in comparison with that of non- or monoacylated hydrazines, it reacted under various conditions with a representative set of ketones to give the corresponding hydrazones in high yields. The aliphatic hydrazones were readily reduced to hydrazines with NaBH4, whereas the aromatic analogues for smooth reduction required the more powerful NaBH3CN. With one exception all the new compounds were crystalline and stable under normal conditions. The new reagent and an alkylated derivative retained satisfactory reactivity towards activated isocyanates to provide acyl ureas. Some characteristic features of the MR- and IR-spectra of these novel compounds are briefly discussed.
View MoreContact:86+21-56421993
Address:3F,BUILDING 10,NO.2889 JINKE ROAD, SHANGHAI.
Nantong LiKai Chemical Co.,Ltd
Contact:+86-513-89068669
Address:Jincheng Science Park
Yingkou Sanzheng Organic Chemical Co. Ltd.
Contact:+86-417-3638818
Address:25 Gengxinli Village, Daqing Road, Yingkou, Liaoning, China
Tianjin Derchemist Sci-Tech Co., Ltd.
website:http://www.derchemist.com
Contact:+86-22-58627059
Address:Xinmao Science and Technology Park,Huayuan Industrial Park
Contact:886 2 2541 0022
Address:8 Fl., No. 11, Sec. 1, Chung Shan North Rd., Taipei, Taiwan R.O.C.
Doi:10.1080/17415993.2018.1480725
(2018)Doi:10.1055/s-0036-1588515
(2017)Doi:10.1515/bchm2.1963.333.1.282
(1963)Doi:10.1002/ejoc.201301128
(2014)Doi:10.1039/J19700003303
()Doi:10.1016/S0960-894X(99)00152-3
(1999)