Towards the synthesis of spongistatin 1: Diastereoselective synthesis of the C(36)-C(45) subunit

DOI: 10.1016/S0040-4039(99)00464-5

Source and publish data:

Tetrahedron Letters p. 3351 - 3354 (1999)

Update date:2022-08-02

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Authors:

Micalizio, Glenn C.

Roush, William R.

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Article abstract of DOI:10.1016/S0040-4039(99)00464-5

An efficient and highly diastereoselective 12 step synthesis of the C(36)-C(45) subunit (2a) of spongistatin 1 is described. The synthesis features highly diastereoselective α-alkoxyallylation reactions using the γ-alkoxy substituted allylstannanes 5 and

Full text of DOI:10.1016/S0040-4039(99)00464-5

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