Synthesis of chiral 1,4-dihydropyridines by diastereoface-selective asymmetric addition to nicotinic amides

DOI: 10.1016/S0040-4039(99)00683-8

Source and publish data:

Tetrahedron Letters p. 4231 - 4234 (1999)

Update date:2022-08-03

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Authors:

Yamada, Shinji

Ichikawa, Mayumi

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Article abstract of DOI:10.1016/S0040-4039(99)00683-8

Diastereoface-selective asymmetric addition of organometallic reagents to pyridinium salts of 1 and 2 was performed to give chiral 1,4-dihydropyridines in good regio- and stereoselectivities. The absolute configuration of the newly-produced chiral center

Full text of DOI:10.1016/S0040-4039(99)00683-8

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Product name:3-Pyridinecarboxylic acid, 1,4,5,6-tetrahydro-4-phenyl-, methyl ester, (4S)-

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