Synthesis of 1,2,3-trisubstituted pyrrolo[3,2-c]quinolines via palladium-catalyzed heteroannulation with internal alkynes

Article abstract of DOI:10.1016/S0040-4039(99)00753-4

Various 1,2,3-trisubstituted pyrrolo[3,2-c]quinolines were synthesized by palladium-catalyzed heteroannulation of 4-amino-3-iodoquinoline derivatives and internal alkynes. The 1,2,3-trisubstituted pyrrolo[3,2- c]quinolines could be further transformed by