A new approach to the synthesis of N-protected 2- and 5-substituted 3-halopyrroles

Article abstract of DOI:10.1055/s-1995-3893

A new and efficient method for the preparation of N-protected 5- and 2-substituted 3-bromopyrroles 15 and 16 via acid-catalyzed cyclization of the corresponding acetylenic ketones 6 and acetylenic acetals 14 has been found (Scheme 3). Using this methodolo