Bioorganic and Medicinal Chemistry Letters p. 1505 - 1510 (1999)
Update date:2022-08-03
Topics:
Dang, Qun
Brown, Brian S.
Van Poelje, Paul D.
Colby, Timothy J.
Erion, Mark D.
A new prodrug approach for intracellular delivery of phosphonates was developed via the synthesis of 3-phthalidyl esters of 1- naphthalenemethylphosphonate. This approach is advantageous over the traditional acyloxymethyl phosphonate prodrugs, because the
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