The preparation of 4,5-dihydro-3-aryl-naphth-[1,2-c]-isoxazoles from dilithiated 1-tetralone oxime and aromatic esters

Article abstract of DOI:10.1080/00397910008086979

Dilithiated 1-tetralone oxime was prepared in excess lithium diisopropylamide and condensed with a variety of esters followed by acid cyclization of C-acylated intermediates to substituted 4,5-dihydronaphth-[ 1,2-c]-isoxazoles.

Full text of DOI:10.1080/00397910008086979

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Synthetic Communications: An
International Journal for Rapid
Communication of Synthetic
Organic Chemistry
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The Preparation of 4,5-
Dihydro-3-Aryl-Naphth-[1,2-c]-
Isoxazoles From Dilithiated 1-
Tetralone Oxime and Aromatic
Esters
Charles F. Beam a , Deborah A. Schady a , Kelly
L. Rose a , Wayne Kelley Jr. a , Ronjay Rakkhit a
, Christopher D. Hornsby a & Shannon L. Studer-
Martinez a
a Department of Chemistry and Biochemistry ,
College of Charleston Charleston , South Carolina,
29424
Published online: 04 Dec 2007.
To cite this article: Charles F. Beam , Deborah A. Schady , Kelly L. Rose , Wayne
Kelley Jr. , Ronjay Rakkhit , Christopher D. Hornsby & Shannon L. Studer-Martinez
(2000) The Preparation of 4,5-Dihydro-3-Aryl-Naphth-[1,2-c]- Isoxazoles From
Dilithiated 1-Tetralone Oxime and Aromatic Esters, Synthetic Communications: An
International Journal for Rapid Communication of Synthetic Organic Chemistry, 30:18,
3391-3404, DOI: 10.1080/00397910008086979
To link to this article: http://dx.doi.org/10.1080/00397910008086979
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