Asymmetric synthesis of polyacetate derived building clocks with α- oxyanion functionality. Lewis acid catalyzed opening of 2,9- dioxabicyclo[3.3.1]nonan-3-ones

Article abstract of DOI:10.1016/S0040-4020(99)00460-3

All four stereoisomeric cyclic 3,5,7-trihydroxyheptanoic acid equivalents of the polyacetate aldol type (Scheme 1) are obtainable from 8- oxabicyclo[3.2.1]oct-6-en-3-one which functions as a meso-configurated 4-way optical switch. Lewis acid assisted nucl