Biomimetic synthesis of the neolignans kadsurenone, denudatin B, O- methyl-liliflodione, and liliflol B

Article abstract of DOI:10.1016/S0040-4039(99)01063-1

Synthesis of (±)-kadsurenone (1), (±)-denudatin B (2), (±)-O-methyl- liliflodione (3a), and (±)-liliflol B (14) is described. The key synthetic step is a biomimetic cationic cycloaddition between E- or Z-1,2-dimethoxy-4- propenylbenzene (11) and ortho-qui