Synthesis of a calix[5]arene receptor having two benzoic acid moieties

Article abstract of DOI:10.1016/S0040-4039(99)01289-7

Synthesis and binding behavior of a calix[5]arene receptor possessing two benzoic acids are reported. Two water molecules were bound within the cavity by hydrogen bonding interaction between the two carboxylic acids of the receptor. It also binds 2-aminopyrimidine to form a complex in which the aromatic ring of the guest resides deeply within the cavity.