6-endo,6-endo,6-exo cascade cyclization starting from vinyl radical; construction of a dodecahydrophenanthrene system

DOI: 10.1016/S0040-4039(99)01234-4

Source and publish data:

Tetrahedron Letters p. 6277 - 6280 (1999)

Update date:2022-08-03

Topics:

Authors:

Takasu, Kiyosei

Kuroyanagi, Jun-ichi

Katsumata, Akira

Ihara, Masataka

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/S0040-4039(99)01234-4

Treatment of 1-iodo-1,5-diene 3 with Bu₃SnH at 80°C afforded the 6- endo cyclized product 6. The reaction was extended further to achieve the transformation of 1-iodo-1,5,9,14-tetraene 10 into dodecahydrophenanthrene 11 under one electron reductive conditions via 6-endo,6-endo,6-exo cascade cyclization.

Full text of DOI:10.1016/S0040-4039(99)01234-4

Products guided by the article

Product name:tert-butyl-dimethyl-[4-(6-methyl-cyclohex-2-enyl)-butoxy]-silane

Cas No:247171-79-5

R&D Labs maybe for 247171-79-5

MiHecb Bio-Tech Co., Ltd.

Contact:+86-0592 5353131

Address:No.56 Guani Road Software Park 2,Siming District
Santow Laboratory Limited

Contact:+86-371-55981030

Address:Room 1571, Macalline Soho, No.1, Shangdu Road, Zhengzhou, Henan
Jiangsu Dacheng Pharmaceutical and Chemical Co.,Ltd

Contact:+86-0517-87036900

Address:Chuzhou Chemical park, Huai'an, Jiangsu Province
Zhejiang Tianyu Pharmaceutical Co., Ltd.

Contact:+86-576-84177669, 89189665,89189688,84168770

Address:Jiangkou Development Zone, Huangyan, Taizhou City, Zhejiang
SHIFANG SUHONG CHEMICAL CO.,LTD

Contact:+86-838-2224563

Address:Room 1207 Zongchen Sunshine No.128 Taishan South Road,Deyang City,Sichuan China

Relevant to this article

Doi:10.1021/jm00336a045
(1964)
Exploring the chiral space within the active site of α-thrombin with a constrained mimic of D-Phe-Pro-Arg - Design, synthesis, inhibitory activity, and X-ray structure of an enzyme-inhibitor complex

Doi:10.1016/S0960-894X(99)00669-1
(2000)
Synthesis of 9-Dechlorochrysophaentin A Enables Studies Revealing Bacterial Cell Wall Biosynthesis Inhibition Phenotype in B. subtilis

Doi:10.1021/jacs.0c04917
(2020)
Doi:10.1007/BF00906674
(1979)
Stereospecific synthesis and biological evaluation of monodesmethyl metabolites of (+)-13a-(S)-deoxytylophorinine as potential antitumor agents

Doi:10.1055/s-0032-1316810
(2012)
Synthesis, vibrational, electrostatic potential and NMR studies of (E and Z) 1-(4-chloro-3-nitrophenyl)-3-(2-methoxyphenyl)triazene: Combined experimental and DFT approaches

Doi:10.1016/j.molstruc.2016.06.053
(2016)

Article Doi