Site-specific RNA cleavage using terpyridine · Cu(II)-linked 2'-O- methyloligonucleotides

DOI: 10.1080/07328319908044769

Source and publish data:

Nucleosides and Nucleotides p. 1503 - 1505 (1999)

Update date:2022-08-04

Topics:

Authors:

Inoue, Hideo

Shimizu, Masaki

Furukawa, Takako

Tamura, Takashi

Matsui, Miwa

Ohtsuka, Eiko

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Article abstract of DOI:10.1080/07328319908044769

2'-Deoxy- and 2'-O-methyl-5'-O-terpyridyl derivatives of adenosine and cytidine were synthesized and used to construct 5'-end-modified oligonucleotides. These antisense agents complexed with Cu(II) exclusively cleaved a complementary RNA oligomer at the s

Full text of DOI:10.1080/07328319908044769

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