Synthesis and antimalarial activity of dldeoxyfebrifugine

DOI: 10.3987/COM-99-8564

Source and publish data:

Heterocycles p. 1869 - 1875 (1999)

Update date:2022-09-26

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Authors:

Takeuchi, Yasuo

Tokuda, Shin-Ichiro

Takagi, Tomoko

Koike, Midori

Abe, Hitoshi

Harayama, Takashi

Shibata, Yasuharu

Kim, Hye-Sook

Wataya, Yusuke

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Article abstract of DOI:10.3987/COM-99-8564

dl-Deoxyfebrifugine (3) was synthesized from 2-piperidone (4) by two methods via the Wittig reaction of 2-hydroxypiperidine (6). The antimalarial activity of 3 was discussed.

Full text of DOI:10.3987/COM-99-8564

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