Reactions of uracils, 24. Multiple anellation to uracils and their analogs - An approach to Nevirapine-type tricycles

Article abstract of DOI:10.1080/00397919908085913

Starting with 6-amino-1,3-dimethyluracil 1 a structural analog of the NNRTI Nevirapine 16 is synthesized in a sequence of two ring anellations and a Beckmann rearrangement. The anellation behavior of 3 is studied in general leading to the anellated systems 5, 7a-c, 12 a-c.

Full text of DOI:10.1080/00397919908085913

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Synthetic Communications: An
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Reactions of Uracils, 24. Multiple
Anellation to Uracils and their
Analogs - An Approach to
Nevirapine-Type Tricycles
Heinrich Wamhoff a , Christian Sattler a , Pál Sohár b & János
Rohonczy b
a Kehrlé-Institut für Organische Chemie und Biochemie
der Universität Bonn , Gerhard-Domngk-Str. 1, 0-53121,
Germany Fax: E-mail:
b Eötvös Loránd University, Deportment of General and
Inorganic Chemistry , Pázmány Péter Sétány 1, H-1117,
Budapest, Hungary
Published online: 17 Sep 2007.
To cite this article: Heinrich Wamhoff , Christian Sattler , Pál Sohár & János Rohonczy (1999)
Reactions of Uracils, 24. Multiple Anellation to Uracils and their Analogs - An Approach to
Nevirapine-Type Tricycles, Synthetic Communications: An International Journal for Rapid
Communication of Synthetic Organic Chemistry, 29:22, 3919-3937
To link to this article: http://dx.doi.org/10.1080/00397919908085913
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