Construction of sequence-selective peptide receptors from conformationally restricted eta- and theta-amino acids

Article abstract of DOI:10.1016/S0960-894X(99)00463-1

Oligomeric chemoreceptors for tripeptides have been constructed from a set of novel eta- and theta-amino acids. Screening against an encoded combinatorial tripeptide library has revealed two new small molecule chemoreceptor motifs with highly sequence-selective binding properties.