Synthesis of (11S)- and (11R)-Porphobilinogen; Stereochemical Studies on Hydroxymethylbilane Synthase (PBG Deaminase)

DOI: 10.1039/c39850000924

Source and publish data:

Journal of the Chemical Society. Chemical communications p. 924 - 927 (1985)

Update date:2022-08-04

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Authors:

Neidhart, Werner

Anderson, Paul C.

Hart, Graham J.

Battersby, Alan R.

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Article abstract of DOI:10.1039/c39850000924

(11S)- and (11R)-<11-(2)H1>Porphobilinogen (PBG) are synthesized and their configurations are estabilished by degradation to a derivative of (2)H1-glycine; they are used to prove that when hydroxymethylbilane synthase (PBG deaminase) acts on PBG in the pr

Full text of DOI:10.1039/c39850000924

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