Synthesis of (11S)- and (11R)-Porphobilinogen; Stereochemical Studies on Hydroxymethylbilane Synthase (PBG Deaminase)

DOI: 10.1039/c39850000924

Source and publish data:

Journal of the Chemical Society. Chemical communications p. 924 - 927 (1985)

Update date:2022-08-04

Topics:

Authors:

Neidhart, Werner

Anderson, Paul C.

Hart, Graham J.

Battersby, Alan R.

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1039/c39850000924

(11S)- and (11R)-<11-(2)H1>Porphobilinogen (PBG) are synthesized and their configurations are estabilished by degradation to a derivative of (2)H1-glycine; they are used to prove that when hydroxymethylbilane synthase (PBG deaminase) acts on PBG in the pr

Full text of DOI:10.1039/c39850000924

View Article Online / Journal Homepage / Table of Contents for this issue

View Article Online

Products guided by the article

Product name:3-{5-[((1S,2R)-2-Hydroxy-1-methyl-2-phenyl-ethyl)-methyl-hydrazonomethyl]-4-methoxycarbonylmethyl-1H-pyrrol-3-yl}-propionic acid methyl ester

Cas No:252664-13-4

R&D Labs maybe for 252664-13-4

Xinchang Jiu Xin Pharmaceutical Co., Ltd

website:http://www.jiuxinpharm.com

Contact:86 137 5756 8585

Address:Poyang industry Park
Jiangxi Dongbang Pharmaceutical Co., Ltd.

Contact:+86-795-4433603, 4433388

Address:Fengxin Industrial Park, Fengxin County, Jiangxi Province, P.R.C
Hangzhou GreenCo Science & Technology Co., Ltd.

Contact:86-571-88257303

Address:1713 Room,Jingui Building,Gudun Road,Xihu District,Hangzhou,China
Shanghai agrotree chemical co.,ltd.

Contact:+86-21-50117563

Address:Room 8A,liangfeng building,No.8 dongfang RD.pudong,shanghai,China
Nanjing lanbai chemical Co.,Ltd.

Contact:+86-25-85499326

Address:Room 908, 9F Taiyue Building,No.285 Heyan Road

Relevant to this article

Doi:10.1002/hlca.19490320641
(1949)
A New Building Block for Diels-Alder Reactions in π-Extended Tetrathiafulvalenes: Synthesis of a Novel Electroactive C₆₀-Based Dyad

Doi:10.1021/ol9911674
(1999)
Structure and vibrational assignment of bis(4-amino-3-penten-2-onato) nickel(II). A density functional theoretical study

Doi:10.1016/j.molstruc.2011.05.008
(2011)
A Simple and Versatile Synthesis of Trimethylsiloxy-Substituted Isocyanates

Doi:10.1055/s-1988-27779
(1988)
Ring-opening of 2,3-epoxy-1-propanol with R₃Al: Unprecedented regiochemical switching simply achieved by changing alkyl substituents of aluminium reagent

Doi:10.1016/j.jorganchem.2005.03.069
(2005)
Oxygenated analogues of 1-[2-(diphenylmethoxy)ethyl]- and 1- [2- [bis (4-fluorophenyl)methoxy]ethyl]-4-(3-phenylpropyl)piperazines (GBR 12935 and GBR 12909) as potential extended-action cocaine-abuse therapeutic agents

Doi:10.1021/jm990291q
(1999)

Article Doi