Tetrahedron Letters p. 7911 - 7915 (1999)
Update date:2022-08-03
Topics:
Coleman, Michael P.
Boyd, Mary K.
The 9-phenylthioxanthyl (S-pixyl or S-Px) group has been investigated as a photocleavable protecting group for primary alcohols, and specifically as a 5' hydroxy protecting group for deoxyribonucleosides. Several alcohols, including the four nucleosides with protected exocyclic amino functions, were protected in very good to excellent yield by treatment of 9-chloro-9-phenylthioxanthene 3 in dry pyridine to reveal the derivatized compounds. Irradiation of the protected substrates in neutral, aqueous solution regenerated the starting alcohols in excellent yield.
View MoreHANGZHOU TOYOND BIOTECH CO., LTD
Contact:+86-571-86965177
Address:No. 189, Fengqi East Road, Hangzhou, China
Contact:0027-717-456976
Address:2ND FLOOR, 325 VAUSE ROAD, OVERPORT, 4001, SOUTH AFRICA
Shanghai HengXun Pharmaceutical Tech. Co., Ltd.
Contact:86-86-52730756
Address:Room 603, No. 240, Tianmuzhong Road, Zhabei, Shanghai, China
Golden Union Agrochemical Import and Export Co., Ltd.
Contact:86-755-23910527
Address:Room 1106, Tower 3A, Excellence Century Center, Futian District, Shenzhen, China
Shanghai Yuking Water Soluble Material Tech Co., Ltd
Contact:86-21-68286299
Address:4F, 13B, No. 600, South Xinyuan Road 201306, Shanghai, China
Doi:10.1016/S0022-328X(99)00445-3
(1999)Doi:10.1016/j.molcata.2007.04.031
(2007)Doi:10.1016/S0022-328X(99)00456-8
(1999)Doi:10.1039/jr9650004127
(1965)Doi:10.1016/S0045-6535(99)00325-2
(2000)Doi:10.1007/s10593-006-0168-1
(2006)
