Journal of labelled compounds and radiopharmaceuticals p. 1075 - 1083 (1999)
Update date:2022-08-02
Topics:
Waterhouse, Ian
Diclofenac is a potentially useful substrate for the study of drug-drug interactions caused by modulation of the activity of specific isoforms of cytochrome P450. The synthesis of a deuterium labelled version of its principal human metabolite, 4'-hydroxydiclofenac, for use as an internal standard in LC-MS-MS studies, is described.
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