Efficient radical cyclisation of secondary amides: An enantioselective synthesis of phenyl allokainoid

DOI: 10.1016/S0040-4039(99)00431-1

Source and publish data:

Tetrahedron Letters p. 3487 - 3490 (1999)

Update date:2022-07-30

Topics: Enantioselective synthesis Secondary amides

Authors:

Bryans, Justin S.

Large, Jonathan M.

Parsons, Andrew F.

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/S0040-4039(99)00431-1

Cyclisation of various unsaturated haloamides with tributyltin hydride/AIBN has been explored. Substituted pyrrolidinones were isolated in good to excellent yield and the cyclisation of a serine-derived amide was utilised as the key step in an enantiosele

Full text of DOI:10.1016/S0040-4039(99)00431-1

Products guided by the article

Product name:(3S,4S,5S)-3-Phenyl-4-(ethoxycarbonylmethyl)-5-(tert-butyldiphenylsilyloxymethyl)pyrrolidin-2-one

Cas No:254763-32-1

R&D Labs maybe for 254763-32-1

Shanghai Rainbow Chemistry Co., Ltd.

Contact:+86-21-64968086-5815/5812

Address:3rd floor, Building 7, 251 Faladi Road, Zhangjiang Hi-Tech Park, Pudong District, Shanghai, P.R. China
Hubei Danao Pharmaceutical Co.,Ltd.

website:http://www.danaopharm.com

Contact:+86-719-5251167

Address:Fandan Road,Danjiangkou,Hubei
Shanghai Korey Pharm Co.,Ltd.(expird)

Contact:021-61840961 021-61840962

Address:No.157,Zhuguang Rd, Qingpu, Shanghai, China
Dayang Chem (Hangzhou) Co.,Ltd.

website:http://www.dycnchem.com

Contact:+86-571-88938639

Address:9/F, Unit 2 Changdi Torch Building, 259# WenSan Road, Xihu District, Hangzhou City 310012, P.R.China
Skyrun Industrial Co.,Ltd(expird)

website:http://www.chinaskyrun.com

Contact:0086-576-84610586

Address:Chemical Development Zone

Relevant to this article

Doi:10.1039/j39690002132
(1969)
Synthesis and applications of 3-[6-(hydroxymethyl)pyridin-2-yl]-1,1′- bi-2-naphthols or 3,3′-bis[6-(hydroxymethyl)pyridin-2-yl]-1,1′-bi-2- naphthols

Doi:10.1055/s-2007-983787
(2007)
Synthesis, magnetism, ¹H NMR and redox activity of dicopper(II) complexes having a discrete {Cu₂(μ-phenoxide)₂}²⁺ unit supported by a non-macrocyclic ligand environment. Crystal structure of [Cu₂(L)₂(OCIO₃)₂] [HL = 4-methyl-2,6-bis(pyrazol-1-ylmethyl)-phenol]

Doi:10.1039/a907250k
(1999)
Synthesis and application of novel carbohydrate-based ammonium and triazolium salts

Doi:10.1080/00397911.2019.1625403
(2019)
α-amino acid phenolic ester derivatives: Novel water-soluble general anesthetic agents which allosterically modulate gaba_a receptors

Doi:10.1021/jm010903i
(2001)
Synthesis of an anionic tridentate phosphinoborate and its reaction chemistry with Sn(II)

Doi:10.1039/a906560a
(1999)

Article Doi