Tetrahedron Letters p. 8641 - 8645 (1999)
Update date:2022-08-02
Topics:
Uehara, Hisatoshi
Oishi, Tohru
Yoshikawa, Kazuhiro
Mochida, Kenichi
Hirama, Masahiro
The marine antibiotic korormicin, isolated from the culture filtrate of marine bacterial strain Pseudoalteromonas sp. F-420, specifically inhibits the growth of marine Gram-negative bacteria without affecting terrestrial species. The absolute configuration of korormicin was determined by the combination of a CD exciton chirality method and chemical degradation. Convergent total synthesis of korormicin has been also achieved.
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