Bioorganic and Medicinal Chemistry Letters p. 3147 - 3152 (1999)
Update date:2022-08-03
Topics:
Stuerzebecher, Joerg
Vieweg, Helmut
Steinmetzer, Torsten
Schweinitz, Andrea
Stubbs, Milton T.
Renatus, Martin
Wikstroem, Peter
Synthesis and anti-uPA activity of a series of Nα-triisopropyl-phenylsulfonyl-protected 3-amidino-phenylalanine amides are described. We have explored SAR around the C-terminal amide part for inhibition of uPA, plasmin and trypsin. Modification of the ami
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