Stereoselective synthesis of β-sultams using chiral tricarbonyl(η6- arene)chromium(0) complexes

Article abstract of DOI:10.1016/S0040-4020(99)00875-3

The reaction of (-)1R or (+)-1S-tricarbonyl(2-substituted benzaldehyde)chromium complexes with tertbutylmethanesulfonamide dianion afforded, after decomplexation and intramolecular cyclization, the enantiomerically pure N-tert-butyl-3-(2-phenyl substituted)1,2-thiazetidine 1,1 dioxide derivatives. The hydrolytic ring opening gave the corresponding enantiopure β-aminosulfonic acid.