Tetrahedron Letters p. 8969 - 8970 (1999)
Update date:2022-08-04
Topics:
Buhr, Chris A.
Matteucci, Mark D.
Froehler, Brian C.
A tetracyclic 2'-deoxyadenosine has been synthesized via a Stille biaryl coupling on a protected 6-chloro-7-deaza-7-iodopurine-2'-deoxyribose followed by cyclization. The nucleoside was incorporated into an oligodeoxynucleotide (ODN) and shown to pair with thymine.
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