Incorporation of 2'-deoxysangivamycin in DNA duplexes: The conversion of a pyrrolo[2,3-d]pyrimidine nitrile to a carboxamide upon oligonucleotide deprotection

Article abstract of DOI:10.1080/07328319908044635

Oligonucleotides containing 2'-deoxysangivamycin are described. The phosphoramidite of 2'-deoxytoyocamycin was prepared and used in solid-phase synthesis. Upon deprotection the pyrrolo[2,3-d]pyrimidine nitrile residues were converted to carboxamides. Acco

Full text of DOI:10.1080/07328319908044635

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Nucleosides and Nucleotides
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Incorporation of 2′-Deoxysangivamycin
in DNA Duplexes: The Conversion of
a Pyrrolo[2, 3-d]Pyrimidine Nitrile to
a Carboxamide upon Oligonucleotide
Deprotection
Frank Seela a & Matthias Zulauf a
a Laboratorium für Organische und Bioorganische Chemie, Institut
für Chemie, Universität Osnabrück , Barbarastr. 7, D-49069,
Osnabrück, Germany
Published online: 04 Oct 2006.
To cite this article: Frank Seela & Matthias Zulauf (1999) Incorporation of 2′-Deoxysangivamycin
in DNA Duplexes: The Conversion of a Pyrrolo[2, 3-d]Pyrimidine Nitrile to a Carboxamide
upon Oligonucleotide Deprotection, Nucleosides and Nucleotides, 18:11-12, 2697-2709, DOI:
10.1080/07328319908044635
To link to this article: http://dx.doi.org/10.1080/07328319908044635
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