Angewandte Chemie - International Edition p. 377 - 380 (2000)
Update date:2022-08-05
Topics:
Paterson, Ian
Florence, Gordon J.
Gerlach, Kai
Scott, Jeremy P.
With a similar mechanism of action to taxol, the title compound 1 is a particularly promising candidate for development in cancer chemotherapy. This efficient synthesis, based on stereocontrolled aldol reactions, should help to overcome the scarce natural
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