An efficient method for preparing the α-deuterated-α,β-unsaturated carbonyl compounds by reaction of stable phosphonium ylides with carbonyl compounds in deuterium oxide

Article abstract of DOI:10.1080/00397910008087298

Carbonyl compounds reacted with stable phosphonium ylides in D₂O to give α-deuterated-α,β-unsaturated carbonyl compounds in the same flask. The chemical yield and deuterium incorporation are excellent under our procedure. The fragile group like

Full text of DOI:10.1080/00397910008087298

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Synthetic Communications: An
International Journal for Rapid
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Organic Chemistry
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An Efficient Method
for Preparing the α-
Deuterated-α,β-Unsaturated
Carbonyl Compounds
by Reaction of Stable
Phosphonium Ylides with
Carbonyl Compounds in
Deuterium Oxide
Yung-Son Hon a , Tzyy-Rong Sheu a & Chia-Fu Lee a
a Department of Chemistry, National Chung-Cheng
University, Chia-Yi, Taiwan, 621, Republic of China
Version of record first published: 04 Dec 2007.
To cite this article: Yung-Son Hon, Tzyy-Rong Sheu & Chia-Fu Lee (2000): An Efficient
Method for Preparing the α-Deuterated-α,β-Unsaturated Carbonyl Compounds by
Reaction of Stable Phosphonium Ylides with Carbonyl Compounds in Deuterium Oxide,
Synthetic Communications: An International Journal for Rapid Communication of
Synthetic Organic Chemistry, 30:1, 97-118
To link to this article: http://dx.doi.org/10.1080/00397910008087298
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