Bioorganic and medicinal chemistry letters p. 1625 - 1628 (2000)
Update date:2022-08-02
Topics:
Nantermet
Barrow
Selnick
Homnick
Freidinger
Chang
O'Malley
Reiss
Broten
Ransom
Pettibone
Olah
Forray
A series of alpha1a receptor antagonists derived from a 4-aryl-3,4-dihydropyridine-2-one heterocycle is disclosed. Potency in the low nanomolar to picomolar range along with high selectivity was obtained. In vivo efficacy in a prostate contraction model in rats was observed with a few derivatives.
View MoreTai zhou world Pharm & Chem Co., Ltd
Contact:+86-576-85301198
Address:Rome 1001,wangjiang plaza,unti 2,jinshan east Road linhai,zhejiang,china
Suzhou Jingye Medicine & Chemical Co., Ltd
website:http://www.jingyechem.cn
Contact:+86-512-66658588
Address:No. 88, Sanlian Street, Jinfeng Road, Suzhou New District, Jiangsu Province, P. R. China
Shandong Dayi Chemical Co., Ltd.
website:http://www.dayi.com.cn
Contact:+86- 535-7388728. 15306386031
Address:No 1 Danya west road, Laiyang City, Shandong province
Contact:+86-575-82733999 0575-82732999
Address:hangzhou gulf fine chemical zone,shangyu city,zhejiang province
SHANGHAI T&W PHARMACEUTICAL CO., LTD.
website:http://www.trustwe.com
Contact:+86-21-61551611
Address:601, No. 1, 2277 Nong, Zu Chongzhi Road, Zhangjiang Hightech. Park, Pudong
Doi:10.1016/S0957-4166(00)00443-2
(2000)Doi:10.1007/BF00590809
(1963)Doi:10.1021/ja992648l
(2000)Doi:10.1016/S0020-1693(99)00497-1
(2000)Doi:10.1002/jhet.5570370101
(2000)Doi:10.1021/jo990776m
(1999)