Bioorganic and medicinal chemistry letters p. 1625 - 1628 (2000)
Update date:2022-08-02
Topics:
Nantermet
Barrow
Selnick
Homnick
Freidinger
Chang
O'Malley
Reiss
Broten
Ransom
Pettibone
Olah
Forray
A series of alpha1a receptor antagonists derived from a 4-aryl-3,4-dihydropyridine-2-one heterocycle is disclosed. Potency in the low nanomolar to picomolar range along with high selectivity was obtained. In vivo efficacy in a prostate contraction model in rats was observed with a few derivatives.
View MoreShuanghe Bio-Technology Limited(expird)
Contact:+86-571-61710758,18968016640
Address:Jinqiao north road 916# Fuyang
Hangzhou Ledun Technology Co.,Ltd.
Contact:86-571-18767088918
Address:No.6 street,XiaSha,Hangzhou,China.
Anhui New Star Pharmaceutical Development Co., Ltd
Contact:013956922763
Address:Floor 3, F9A, F Workshop, No.110 Kexue Road, High-Tech Development Zone, Hefei, Anhui ,China
Jiangsu Wanlong Chemical Co., Ltd.
website:http://www.wanlongchem.com
Contact:+86-511-86810993 0086-511-8681 0888;
Address:Quanzhou Town, Danyang City, Jiangsu
Landz International Company Ltd.
Contact:0086-21-58891610
Address:985 Dongfang Road, Pudong, Shanghai 200122 China
Doi:10.1016/S0957-4166(00)00443-2
(2000)Doi:10.1007/BF00590809
(1963)Doi:10.1021/ja992648l
(2000)Doi:10.1016/S0020-1693(99)00497-1
(2000)Doi:10.1002/jhet.5570370101
(2000)Doi:10.1021/jo990776m
(1999)