Synthetic Communications p. 1543 - 1553 (2000)
Update date:2022-08-04
Topics:
Felfoeldi, Karoly
Sutyinszky, Maria
Nagy, Nora
Palinko, Istvan
A series of stereoisomeric o-methoxy-substituted 2,3-diphenyl propenoic acids and their methyl esters have been synthesized. The E isomers were prepared by a modified Perkin condensation (substituted benzaldehyde, phenylacetic acid, Et3N/acetic anhydride). The difficult to access Z isomers were obtained conveniently in good yields when the appropriate coumarin derivatives were allowed to react with KOH and CH3I in DMSO.
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Doi:10.1007/BF01046677
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(1934)Doi:10.1039/b515727g
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