A rational approach to the design and synthesis of a new bradykinin B1 receptor antagonist

DOI: 10.1021/jm990962k

Source and publish data:

Journal of Medicinal Chemistry p. 2387 - 2394 (2000)

Update date:2022-08-04

Topics:

Authors:

Bedos, Philippe

Amblard, Muriel

Subra, Gilles

Dodey, Pierre

Luccarini, Jean-Michel

Paquet, Jean-Luc

Pruneau, Didier

Aumelas, André

Martinez, Jean

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jm990962k

We have previously synthesized a potent and selective B₁ bradykinin receptor antagonist, JMV1645 (H-Lys-Arg-Pro-Hyp-Gly-Igl-Ser-D-BT-OH), containing a dipeptide mimetic ((3S)-amino-5-carbonylmethyl-2,3-dihydro-1,5- benzothiazepin-4(5H)-one (D-B

Full text of DOI:10.1021/jm990962k

Products guided by the article

Product name:1-Boc-4-[(2-phenylethyl)amino]piperidine-4-carboxamide

Cas No:288154-19-8

R&D Labs maybe for 288154-19-8

Jining Shengrun Chemical Industry Co., Ltd.

Contact:+86-537-7121666 ,

Address:West Ring Road,Wenshang County Shandong Province
Changsha Botaniex Inc.

Contact:(86) 731 88718666

Address:Room 1222, Unit 4, Building B, Shangcheng, No.47, Kaiyuan East Road.
Shandong Xingshun New Material Co., Ltd.

website:http://www.sd-xingshun.com

Contact:+86-519-86461196/+86-519-86464994

Address:Middle of Luhua East Road, Dingtao District
Synchemie Co., Ltd.

website:http://www.synchemie.com/

Contact:+86-574-87642758

Address:Room 901, Yinyi Bund Building， 132 Renmin Road
HEBEI BRANT PHARMACEUTICAL

Contact:+86-0311-84455288-844

Address:Mayu Industrial Park, Jinzhou, Hebei, China.

Relevant to this article

Cyclization of alkenyl radicals in 5- and 6-(π-exo)-exo-dig modes: New entry to exo-cyclic dienes

Doi:10.1021/ol005785s
(2000)
Identification of new Cdc25 dual specificity phosphatase inhibitors in a targeted small molecule array

Doi:10.1016/S0968-0896(00)00069-9
(2000)
Facile synthesis and molecular structure of [Ni(PPh₂NHPh)₄]

Doi:10.1002/1521-3749(200007)626:7<1591::AID-ZAAC1591>3.0.CO;2-D
(2000)
Doi:10.2165/00003495-200161020-00006
()
Carbamate-appended N-alkylsulfonamides as inhibitors of γ-secretase

Doi:10.1016/j.bmcl.2007.11.102
(2008)
Introduction of bulky tert-butyl substituents on the core of N,N′-diaryl N-heterocyclic carbenes through the corresponding vicinal diamines

Doi:10.1016/j.tetlet.2013.06.132
(2013)

Article Doi