α-Halogenoacetanilides as hydrogen-bonding organocatalysts that activate carbonyl bonds: Fluorine versus chlorine and bromine

DOI: 10.1002/chem.201303662

Source and publish data:

Chemistry - A European Journal p. 2849 - 2859 (2014)

Update date:2022-08-05

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Authors:

Koeller, Sylvain

Thomas, Coralie

Peruch, Frederic

Deffieux, Alain

Massip, Stephane

Leger, Jean-Michel

Desvergne, Jean-Pierre

Milet, Anne

Bibal, Brigitte

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Article abstract of DOI:10.1002/chem.201303662

α-Halogenoacetanilides (X=F, Cl, Br) were examined as H-bonding organocatalysts designed for the double activation of Ci￡O bonds through NH and CH donor groups. Depending on the halide substituents, the double H-bond involved a nonconventional Ci-H×××O in

Full text of DOI:10.1002/chem.201303662

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