Discovery of 6,11-ethano-12,12-diaryl-6,11-dihydrobenzo[b]quinolizinium cations, a novel class of N-methyl-D-aspartate antagonists

DOI: 10.1021/jm00001a006

Source and publish data:

Journal of Medicinal Chemistry p. 21 - 27 (1995)

Update date:2022-07-29

Topics:

Authors:

Subramanyam

Mallamo Mallamo

Dority Jr.

Earley Earley

Kumar Kumar

Aimone Aimone

Ault Ault

Miller Miller

Luttinger

DeHaven-Hudkins

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jm00001a006

6,11-Ethano-12,12-diaryl-6,11-dihydrobenzo[b]quinolizinium cations 8, a novel class of N-methyl-D-aspartate (NMDA) antagonists acting at the phencyclidine site, have been identified. Structure-activity relationship studies around the lead compound 8a led

Full text of DOI:10.1021/jm00001a006

Products guided by the article

Product name:Benzene, 1,1'-ethenylidenebis[3-bromo-

Cas No:29265-85-8

R&D Labs maybe for 29265-85-8

Tianjin Pharmacn Medical Technology Co.,Ltd.

Contact:86-22-60122566ext.866(English),23359620

Address:Green Industrial Base, 6 Haitaifazhan Sixth Rd., Huayuan Industrial Area, Tianjin, 300384, China
Shanghai Bojing Chemical Co., Ltd.

Contact:021-37122233

Address:6F Buildiing 11,No.388,Baifu Road,District Fengxian.Shanghai, China.
Jiangsu Zhenfang Chemical CO.,LTD.(Suzhou Zhenfang Chemical Factory)

Contact:+86-512-69598882

Address:Room1201, Jiayuan Road No.1018, Xiangcheng District, Suzhou, China
Hangzhou Ocean Chemical Co., Ltd.

website:http://www.hzoceanchem.com

Contact:+86-571-88025872, 28272092, 28272096

Address:Room 623 ,Building No 1 , COFCO Radius Commercial Center Xiwen Road, Xiacheng District, Hangzhou, Zhejiang Province, China
Changyi Xinxing Technology Development Co., Ltd.

Contact:0086-510-86651065(Time Zone:8),86651656

Address:94 Yingbinxilu WestRoad, Huangtu Town, Jiangyin City, Jiangsu, China

Relevant to this article

Evolution from Tunneling to Hopping Mediated Triplet Energy Transfer from Quantum Dots to Molecules

Doi:10.1021/jacs.0c07727
(2020)
Versatile iridicycle catalysts for highly efficient and chemoselective transfer hydrogenation of carbonyl compounds in water

Doi:10.1002/chem.201403701
(2014)
Cyclohexanedione bisaminals as intermediates for cyclen, homocyclen, and cyclam synthesis

Doi:10.1080/00397910600910633
(2006)
Thiazolium ylide-catalyzed intramolecular aldehyde-ketone benzoin-forming reactions: Substrate scope

Doi:10.1002/adsc.200404092
(2004)
Doi:10.1039/jr9360001480
(1936)
Construction of reversible hydration-dehydration system by a model compound and a novel polymer bearing vicinal tricarbonyl structure

Doi:10.1002/pola.24656
(2011)

Article Doi