Monatshefte fur Chemie p. 455 - 459 (1996)
Update date:2022-08-02
Topics:
Abdel-Rahman
Pedersen
Nielsen
N2-Substituted 5-methylisocytidine derivatives were synthesized from S2-methyl-2-thiothymine either by direct substitution of the methylthio group by an amino group and subsequent condensation with 1,2,3,5-tetra-O-acetyl-β-D-ribofuranose to give the acetylated nucleoside or by the opposite sequence first preparing an acetylated 5,S2-dimethyl-2-thiouridine followed by treatment with the appropriate amine.
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(2003)Doi:10.1021/om970118x
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