Tetrahedron p. 1079 - 1086 (1982)
Update date:2022-08-03
Topics:
Tolbert, Laren M.
Siddiqui, Shahabuddin
The regiochemistry observed upon arylation of ambident carbanions by phenyl radicals can be readily explained by consideration of the site of greatest basicity.Thus 1,3-diphenylindenyl anion is arylated to give predominantly 1,1,3-triphenylindene despite the presumed greater stability of the intermediate leading to 1,2,3-triphenyl indene, that is, the 1,2,3-triphenylisoindene radical anion.This explanation may also account for the preference of C-alkylation rather than O-alkylation of nitrocarbanions and for the absence of O-arylation in the SRN1 arylation of enolates.The lack of reactivity of other carbanions is rationalized on thermodynamic grounds.
View MoreChengdu Pukang Biotechnology Co., Ltd
website:http://www.pu-kang.com
Contact:86-028-63976226
Address:No. 868 Xiwang Road,Xinjin county,Chengdu city, China
Anhui Qingyun Pharmaceutical and Chemical Co.,Ltd
Contact:+86-551-63633067
Address:Shuangfeng Road Hefei Anhui
Shanghai Forever Biotech Co., Ltd.
Contact:+86-21-69734790
Address:Room 5017/5019、5022、5024 of Technology Innovation Centre, No.1155, Gongyuan East Rd, QingPu District, Shanghai China.
Beijing Mesochem Technology Co.,LTD
website:http://www.mesochem.com
Contact:0086-10-57862036
Address:2301, Floor 23, Building 9 Lippo Plaza, Yard 8 Ronghua Middle Road, ETDZ, Beijing, China
Suzhou Chiral Pharmaceuticals Co., Ltd.
Contact:86-0512-63197058
Address:Building A, No. 2358, Chang'an Road, Wujiang Science Park
Doi:10.1039/c7ob00499k
(2017)Doi:10.1016/S0040-4020(00)00745-6
(2000)Doi:10.1007/BF02853955
()Doi:10.1021/jm000305o
(2000)Doi:10.1007/BF00909234
(1971)Doi:10.1039/jr9650000012
(1965)