Bioorganic and Medicinal Chemistry Letters p. 2287 - 2289 (2000)
Update date:2022-07-31
Topics:
Savy, Pascal
Benhida, Rachid
Fourrey, Jean-Louis
Maurisse, Rosalie
Sun, Jian-Sheng
A short route to pyrimidine locked nucleosides has been developed for their incorporation in triplex forming oligonucleotides (TFO). Compared to oligonucleotides built with standard nucleosides, the modified TFOs containing 3'-endo blocked residues formed
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