Reaction of 5-aminopyrazole derivatives with ethoxymethylene- malononitrile and its analogues

DOI: 10.1002/jhet.5570310140

Source and publish data:

Journal of Heterocyclic Chemistry p. 239 - 243 (1994)

Update date:2022-07-30

Topics:

Authors:

Nagahara

Kawano Kawano

Sasaoka Sasaoka

Ukawa Ukawa

Hirama Hirama

Takada Takada

Cottam Cottam

Robins Robins

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1002/jhet.5570310140

A one-pot synthesis using 5-aminopyrazole derivatives 1 with ethoxymethylenemalononitrile (EMMN), ethyl ethoxymethylenecyanoacetate (EMCA) or diethyl ethoxymethylenemalonate (DEMM) gave pyrazolo-[1,5-a]pyrimidine compounds 2,4,8. Also, the one step reaction of EMCA with hydrazine hydrate afforded ethyl(4-ethoxycarbonyl-5-pyrazolyl)aminomethylenecyanoacetate 3c. On the other hand, the reaction of 1-substituted 5-aminopyrazole-4-carboxamide 9 with EMMN afforded pyrazolo[3,4-d]pyrimidine compounds 10.

Full text of DOI:10.1002/jhet.5570310140

Products guided by the article

Product name:ethyl-(E/Z)-5-(2-carbethoxy-2-cyanoethenyl)aMino-1H-pyrazole-4-carboxylate

Cas No:321571-07-7

R&D Labs maybe for 321571-07-7

TAIZHOU XINGCHENG CHEMPHARM CO.,LTD.

Contact:0086-0576-88551200,88886292 ,88880039

Address:B Area. 10 Floor.Yaodadasha. 289#.Shifu Road.Taizhou.Zhejiang.China
Rely Chemicals Ltd.

Contact:+86-518-81061113

Address:No. 8 Lingzhou Road, Lianyungang, Jiangsu, China
Anyang Double Circle Auxiliary CO.,LTD

Contact:0086-134 6082 4403

Address:dongfeng road, anyang city, henan province,china
Henan Techway Chemical Co.,Ltd.

website:http://www.techwaychem.com

Contact:+86-371-66380080

Address:No.27 Shunhe Road,
Hangzhou Chemfar Ltd.

Contact:+86-571-87859231, 87859237, 87859239

Address:1606,Huarong Times Mansion, No.3880 Jiangnan Avenue, Binjiang District, Hangzhou, China, 310053

Relevant to this article

A comparative study of the epoxidation of 2-substituted isoflavones by dimethyldioxirane, sodium hypochlorite, and alkaline hydrogen peroxide (Weitz-Scheffer reaction)

Doi:10.1002/jhet.5570370507
(2000)
A facile regio- and stereoselective synthesis of mannose octasaccharide of the N-glycan in human CD2 and mannose hexasaccharide antigenic factor 13b

Doi:10.1016/S0008-6215(01)00307-X
(2002)
Doi:10.1016/S0008-6215(00)81542-6
(1971)
Reduction of adamantanone: Face selection induced by 4-Halo and 4,9-Dihalo substitution

Doi:10.1021/jo9601066
(1996)
Photochemical Behavior of Δ⁴-3-Oxo, Δ⁵-7-Oxo, and Δ¹-3-Oxo Steroids in Concentrated Acid Solution

Doi:10.1021/jo00245a013
(1988)
Doi:10.1016/S0040-4039(01)88435-5
(1969)

Article Doi