Synthesis and evaluation of new 4(3H)-Quinazolinone derivatives as potential anticancer agents

DOI: 10.1016/j.molstruc.2019.127097

Source and publish data:

Journal of Molecular Structure (2020)

Update date:2022-08-05

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Authors:

Gatadi, Srikanth

Pulivendala, Gauthami

Gour, Jitendra

Malasala, Satyaveni

Bujji, Sushmitha

Parupalli, Ramulu

Shaikh, Mujahid

Godugu, Chandraiah

Nanduri, Srinivas

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Article abstract of DOI:10.1016/j.molstruc.2019.127097

A series of new 4(3H)-quinazolinones were synthesized and evaluated for their cytotoxic activity against a set of human cancer cell lines MDA-MB-231 and MCF-7 (breast), HCT-116 and HT-29 (colon) and A549 (lung). Among the tested compounds, 22a exhibited p

Full text of DOI:10.1016/j.molstruc.2019.127097

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