Chemical and Pharmaceutical Bulletin p. 1733 - 1736 (1992)
Update date:2022-08-05
Topics: Solvent Deprotonation Temperature Workup Base Nucleophilic Attack
Kita
Shibata
Yoshida
Tohjo
3-(1-tert-Butyldimethylsiloxy)ethyl-4-sulfinylazetidin-2-one was reacted with silylated N-, S-, O-, and P-nucleophiles in the presence of a catalytic amount of ZnI2 to give the corresponding trans-4-heterofunction-substituted azetidin-2-ones in high yields.
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