Bioscience, Biotechnology and Biochemistry p. 167 - 171 (2001)
Update date:2022-09-26
Topics:
Tsujimori
Mori
BE-40644 is a tetracyclic metabolite of Actinoplanes sp. A 40644 possessing a sesquiterpene-substituted p-benzoquinone structure with cis-fused B/C ring stereochemistry that inhibits the human thioredoxin system as the well as the growth of several cancer cell lines. Its B/C trans-fused stereoisomer at C-6a was synthesized as a racemate starting from geranylacetone and 3,5-dihydroxybenzoic acid.
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(2001)Doi:10.1055/s-2004-831319
(2004)Doi:10.1007/BF00909938
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(1971)Doi:10.1007/BF00909810
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