Journal of the Chemical Society. Perkin transactions II p. 2415 - 2418 (1993)
Update date:2022-08-03
Topics:
Lee, Ikchoon
Lee, Young Sook
Huh, Chul
Lee, Hai Whang
Lee, Byung Choon
The nucleophilic substitution reactions of (Y)-indan-2-yl (Z)-arenesulfonates with (X)-anilines in methanol at 55.0 deg C are reported.Sign reversals in all three second-order cross-interaction constants, ρXY, ρYZ and ρXZ, are observed at non-interaction points <*>Z = -0.11 (ρXY = 0), <*>X = -0.02 (ρYZ = 0) and <*>Y = 0.43 (ρXZ = 0) respectively, which have been ascribed to an unusually large third-order cross-interaction constant, ρXYZ = -0.53, for the reaction series.An SN2 transition state with a tilted, parallel stacked and displaced structure of the three benzene rings in the nucleophile (X), substrate (Y) and leaving group (Z) is proposed to rationalize the strong three-body coupling manifested by the large ρXYZ value.
View MoreGUANGZHOU MEDCAN PHARMATECH LTD
website:http://www.gzmedcan.com
Contact:+86-20-82519649
Address:Building J,Room 101,1 JiangtashanRd,Guang Zhou Science City,Guang Zhou ,China
Beijing Stable Chemcial Co.ltd
Contact:86-10-63785052
Address:A1301 Technological Edifice. No.4 FuFeng Road,FengTai District, Beijing. China
Shanghai Dano Pharmaceutical Co.,Ld.(expird)
Contact:+86-592-6266840
Address:Building 1 Room 512, 720 Cailun Rd, Zhangjiang High-Tech Park, Shanghai 201203, China
BAODING SINO-CHEM INDUSTRY CO.,LTD
Contact:0312-5956088
Address:NO.8 FUXING ROAD,CHINA
Zhejiang Haizhou Pharmaceutical Co., Ltd.
website:https://www.haizhoupharma.com/
Contact:+86-576-88221016
Address:No. 19, Donghai 5th Avenue, Yanhai Industrial Zone, Linhai, Zhejiang, China
Doi:10.1134/S1070363206010208
(2006)Doi:10.1016/S0022-328X(00)90182-7
(1971)Doi:10.1021/acs.orglett.9b01208
(2019)Doi:10.1016/S0040-4039(01)00997-2
(2001)Doi:10.1002/adma.201001221
(2010)Doi:10.1016/S0022-328X(00)00733-6
(2001)
